EINDHOVEN, Netherlands-- PSV Eindhoven's Luciano Narsingh scored a second-half winner as they came from behind to beat Manchester United 2-1 on a night of setbacks for the English side in the Champions League on Tuesday.
United left back Luke Shaw suffered what appeared to be a serious injury and was taken off on a stretcher with an oxygen mask strapped to his face in the early stages of the Group B game.
The match had looked to be heading United's way and their close-season signing from PSV, Memphis Depay, reminded spectators at the Philips Stadium of his prowess with a stunning 41st-minute opener.
PSV, however, caught the visitors napping at a corner in first-half stoppage time as Hector Moreno equalised before a swift break away set up the 57th-minute winner.
"We missed the cutting edge in the final third and didn't make use of opportunities. They punished us with their two main chances," United defender Chris Smalling said.
United set out their stall quickly and took the game to PSV with the 21-year-old Depay, who was warmly welcomed back by the home fans, and teenager Anthony Martial looking dangerous in a two-pronged attack.
Depay's pass set up Martial for a tap-in from close range after just seven minutes but the Frenchman failed to put enough force into the effort.
Shaw's injury came after 15 minutes when a burst of acceleration put him through on goal before he was halted by Moreno's poor challenge, which went unpunished and left the England defender with a suspected broken leg.
The match was halted for eight minutes as medics put Shaw on a stretcher and took him off the pitch.
Depay's goal was a breathtaking display of footwork, set up by fellow Dutchman Daley Blind, who was jeered throughout the game because of his previous connection to Ajax Amsterdam.
As the match went into a lengthy period of stoppage time at the end of the first half, Moreno rose to head home a corner, with Blind helping the ball into his own net.
United dominated exchanges in the second half but were caught out by a sucker punch early on as they pressed high up the pitch.
A searching pass from Andres Guardado in midfield found Maxime Lestienne out on the left and his perfect cross eluded the visiting defence to allow Narsingh to stoop and head home.
Juan Mata should have equalised just after the hour mark but let a brilliant lofted pass from Bastian Schweinsteiger slip under his foot with a goal begging.
